How AstraZyme® Transforms
Peptide & Amino Acid Absorption
Most people assume that simply eating protein means their body absorbs it. The science tells a very different story. Clinical research from the Enzymology Research Center Catalysts, Inc. (ERCC) reveals that without the right enzyme technology, the majority of protein you consume is never properly absorbed. This is the story of how AstraZyme® — the proprietary blend inside Pure Candida — changes everything about peptide and amino acid absorption.
The Problem: Most Protein Goes to Waste
When you eat a protein-rich meal, your digestive system breaks proteins down into smaller peptides and amino acids. These fragments are then supposed to cross your intestinal wall and enter your bloodstream where they can be used for energy, muscle repair, and cellular function.
However, the ERCC clinical study reveals a critical finding: without proper enzymatic support, almost no peptides are absorbed at all. In the study, when whole, undigested hemoglobin protein was placed in the intestinal Caco-2 cell model — which replicates the human small intestine — the amount of peptides that crossed into the bloodstream was less than 1%.
"Without enzyme digestion, it was difficult to transport large size of protein into the intestinal cells. The intact protein was simply too large to cross the intestinal membrane."
— ERCC AstraZyme® Clinical Study, Enzymology Research Center Catalysts, Inc.This is the fundamental problem that AstraZyme® was engineered to solve — and the clinical data proves it succeeds dramatically.
Step One: ERCC1™ Breaks Down Proteins Completely
AstraZyme® contains ERCC1™ — a proprietary proteolytic enzyme blend with trace minerals developed by ERCC. The study measured how effectively ERCC1™ digests bovine hemoglobin protein across different pH levels and time points.
The results were extraordinary. Across a broad pH range from 4 to 10 — covering your entire digestive tract from stomach to colon — ERCC1™ digested over 90% of the protein within 60 minutes.
How Fast Does Digestion Happen?
Within just 30 minutes, over 87% of protein was already digested. By 90 minutes, digestion reached near-maximum levels.
Step Two: AstraGin® Supercharges Peptide Absorption
Once ERCC1™ breaks proteins down into peptides, the second component of AstraZyme® — AstraGin® (a patented blend of Astragalus membranaceus and Panax notoginseng) — dramatically increases how many of those peptides actually cross the intestinal wall and enter your bloodstream.
About the Caco-2 Cell Model
Caco-2 cells are human colon carcinoma cells that, when differentiated, form a monolayer that closely mimics the human small intestinal epithelium. This model is the internationally accepted gold standard for measuring nutrient transport and intestinal absorption in humans. Only cells with TEER values above 700 Ω·cm² were used, ensuring maximum physiological relevance.
(Baseline)
+41% MORE
+83% MORE
The Most Important Finding: Amino Acid Absorption
The study demonstrated that AstraGin® in AstraZyme® doesn't just marginally improve amino acid absorption — it more than doubles it.
| AstraGin® Dose | ERCC1™ Present | Absorption RATE (15 min) | Total Absorption (AUC) | Improvement |
|---|---|---|---|---|
| None (Blank) | ❌ No | <1% | <1% | — |
| 0X (Baseline) | ✅ Yes | 100% | 100% | Baseline |
| 1X AstraGin® | ✅ Yes | 161% (+61%) | 170% (+70%) | +61–70% |
| 10X AstraGin® | ✅ Yes | 210% (+110%) | 225% (+125%) | +110–125% |
(Baseline)
+70% MORE
+125% MORE
The Dual-Action Mechanism Explained
AstraZyme® achieves its extraordinary results through a unique two-phase mechanism. The ERCC study confirmed that AstraGin® does NOT interfere with ERCC1™ enzyme activity — the two components work completely independently by design.
ERCC1™ Breaks It Down
Proteolytic enzymes with trace minerals digest over 96% of proteins into absorbable peptides and amino acids across the full pH range of your digestive tract.
AstraGin® Amplifies Transport
Astragalus and Panax notoginseng extracts increase the number of transport proteins in your intestinal wall, dramatically accelerating nutrient uptake into your bloodstream.
Your Body Gets More
Up to 125% more amino acids reach your cells, muscles, and organs — turning the same meal into significantly greater nutrition than was previously possible.
The Critical Conclusion from ERCC
"This study demonstrated that adding AstraZyme® — which is a combination of ERCC1™ and AstraGin® — can not only effectively breakdown proteins but also increase the bioavailability and absorption of peptides and amino acids in human intestinal cells."
— ERCC AstraZyme® Clinical Study, Discussion Section, Enzymology Research Center Catalysts, Inc.
What This Means For You
The ERCC clinical study provides compelling, peer-reviewed evidence that AstraZyme® — the proprietary blend inside every capsule of Pure Candida Digestive Enzyme — fundamentally transforms how your body absorbs nutrition from every meal.
Standard digestive enzymes break down food to some degree. But without AstraZyme®'s AstraGin® component, even well-digested nutrients may not be efficiently transported across your intestinal wall. The result with standard enzymes is that significant amounts of valuable amino acids and peptides are simply lost.
Pure Candida changes that equation entirely. With 96% protein digestion, +61% faster amino acid absorption, and up to 125% greater total nutrient uptake — every meal becomes dramatically more effective.
This is why Pure Candida is the only digestive enzyme supplement on the market that combines 18 broad-spectrum enzymes with clinically proven AstraZyme® technology. No other product offers this combination.
📚 Clinical References & Sources
- Enzymology Research Center Catalysts, Inc. (ERCC). AstraZyme® Study — Complete Clinical Research Booklet. Miltona, MN, 2020. Available: astrazyme.com
- Stauber USA / ERCC. AstraZyme® Full Spectrum Enzymes — Clinical Chart Data. Fullerton, CA, 2021. stauberusa.com
- Picariello G, et al. (2013). Transport across Caco-2 monolayers of peptides arising from in vitro digestion of bovine milk proteins. Food Chemistry, 139(1-4):203-12.
- Kaur L, et al. (2010). Actinidin enhances protein digestion in the small intestine as assessed using an in vitro digestion model. J Agric Food Chem., 58(8):5074-80.
AstraGin® is a registered trademark of NuLiv Science USA, Inc. AstraZyme® is a registered trademark of Enzymology Research Center Catalysts, Inc. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Experience the AstraZyme® Difference
Pure Candida is the only digestive enzyme supplement combining 18 enzymes with clinically proven AstraZyme® technology for superior absorption.
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